Tuesday, January 7, 2020

Onset of Breast Cancer - 1078 Words

Onset of breast cancer: Introduction: DNA makeup our gene in each cell which control our functions. Gene which increases cell division are called oncogene,others which slow down cell division, or cell die at right time are called tumor suppressor gene.Certain changes or mutation in DNA turn on oncogene or turn off tumor suppressor gene to cause normal breast cell to become cancerous.the stem cell mutation are the actual root of cancer which causes cancer again and again we use different strategies to diagnose the presence of these kind of mutation including different scans including CT scan,ultrasonography,FED. Inherited gene mutations Certain genes that were mutated in parent can dramatically increase the risk of developing certain cancer that run in families. For example BRCA gene are tumor suppressor gene a mutation that can occur in one of these gene in parents cause tumor in progeny, as it no longer suppresses abnormal growth and causes cancerous cell proliferation. (Bahcall O et al.,2013) Genetic testing can diagnose women having inherited mutated gene BRCA1 or BRCA2 tumor suppressor gene. These women can take step to prevent its proliferation. (Goodwin et al.,2009) Mostly high penetrance mutation can cause the development of cancer although many women do not develop the cancer due to high penetrance but can be caused by low penetrance or gene variation causes cancer development. Each of these may have a small individual effect on cancer development, but the overallShow MoreRelatedEssay about Breast Cancer836 Words   |  4 PagesBreast cancer is one of the most widespread cancers among women worldwide. In the US, it is the most common, and the leading cause of cancer related deaths among women between 45 – 64 years of age (Clegg et al., 2002; Ward et al., 2008). Early detection and improved treatment procedures have resulted in gradual decline in the number of deaths caused by the disease since 1990. Nevertheless, in 2009, the estimated death toll for the disease was 40,170 (American Cancer Society, 2009). The gravityRead MoreEssay on Breast Cancer847 Words   |  4 PagesBreast Cancer Chromosome 17 and BRCA1 Among the most common diseases affecting the female population, breast cancer develops in one of every eight American women. This means that almost 200,000 women suffer from the disease each year. Doctors would advise women to take necessary precautions, such as routine surveillance, in order to ensure a life without obtaining this disease prior to understanding any genetic linkage of breast cancer. Although many external factors contribute to breastRead MoreEssay Breast Cancer1675 Words   |  7 PagesBreast Cancer Breast cancer is a disease that is becoming more and more popular in this day of age. One in every eight women is diagnosed with breast cancer (Breast Cancer, 2010). 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